abstract：:Biochemical, physiological and functional studies suggest that the brain renin-angiotensin system (RAS) is regulated independently of the peripheral RAS. Also, all enzymes and peptides necessary for the biosynthesis of various angiotensins have been recognized within the central nervous system. There are divergent opi...

journal_title：Acta neurologica Belgica

authors： Ciobica A,Bild W,Hritcu L,Haulica I

更新日期：2009-09-01 00:00:00

abstract：:We report the case of a 44-year-old woman with chronic facial pain. She was treated with several analgesics, prophylactic medications and infiltrations, but all treatment modalities were ineffective. Finally, the diagnosis of medication-overuse headache complicating migraine without aura was made and an appropriate tr...

journal_title：Acta neurologica Belgica

authors： Debruyne F,Herroelen L

更新日期：2009-09-01 00:00:00

abstract：:Neurosarcoidosis is a diagnostic challenge, especially in the absence of systemic involvement, even when cerebral biopsies show noncaseating granulomas. We report a patient with a pineal germinoma associated with a extensive peri- and intra- tumoural granulomatous reaction, who was first diagnosed as possible neurosar...

journal_title：Acta neurologica Belgica

authors： Visée H,Duprez TP,Godfraind C,Sindic CJ

更新日期：2009-06-01 00:00:00

abstract：:Genistein (4',5,7-trihydroxyisoflavone) is the most abundant isoflavone found in the soybean that exhibits an anti-inflammatory effect. The present study was designed to examine the effects of genistein on expression levels of hemolysate-induced proinflammatory and adhesion molecules in SD rat brain microvascular endo...

journal_title：Acta neurologica Belgica

authors： Lu H,Shi JX,Zhang DM,Chen HL,Qi M,Yin HX

更新日期：2009-03-01 00:00:00

abstract：:The large choice of antiepileptic drugs (AEDs) in Belgium complicates the selection of the appropriate product for the individual patient. International guidelines on the treatment of epilepsy have been published, but are not tailored to the Belgian situation. This publication presents recommendations from a group of ...

journal_title：Acta neurologica Belgica

authors： Boon P,Engelborghs S,Hauman H,Jansen A,Lagae L,Legros B,Ossemann M,Sadzot B,Urbain E,van Rijckevorsel K

更新日期：2008-12-01 00:00:00

abstract：:The Glasgow Coma Scale (GCS) was introduced in 1974 aiming at standardizing assessment of level of consciousness in head injured patients. It has been used mainly in evaluating prognosis, comparing different groups of patients and monitoring the neurological status. However its use expanded beyond the original intenti...

journal_title：Acta neurologica Belgica

authors： Matis G,Birbilis T

更新日期：2008-09-01 00:00:00

abstract：:The primary source of malignant intracerebral nerve sheath tumors is still unclear We report the imaging and MR spectroscopic findings in a 39-year-old man with a very rare brain stem tumor MR examination revealed the presence of intraaxial brain stem tumor with a partial exophytic growth. On pathological examination,...

journal_title：Acta neurologica Belgica

authors： Kozić D,Nagulić M,Samardzić M,Ostojić J,Rasulić L,Cvetković-Dozić D

更新日期：2008-06-01 00:00:00

abstract：:The aim of this study was to investigate personality, by means of the Rorschach Psychodiagnostic test, in a consecutive series of fourteen patients with Parkinson's disease (PD) submitted to bilateral deep brain stimulation of the subthalamic nucleus (DBS STN). Patients were evaluated pre-operatively and 1 year after ...

journal_title：Acta neurologica Belgica

authors： Castelli L,Perozzo P,Caglio M,Rizzi L,Zibetti M,Lanotte M,Lopiano L

更新日期：2008-03-01 00:00:00

abstract：:Catatonia was first described by Kahlbaum in 1874. Ever since, the concept of catatonia has been the focus of debate, a major point of discussion being its nosological status. The question rises whether it is to be considered a syndrome with a wide variety of causes and clinical signs or a distinct clinical entity. Si...

journal_title：Acta neurologica Belgica

authors： Vancaester E,Santens P

更新日期：2007-06-01 00:00:00

abstract：:The ictal bradycardia syndrome is an uncommon diagnosis in which bradycardia is accompanied by simultaneous epileptic discharges in the EEG. We describe a patient who was referred to the emergency ward because of syncope. Ictal semeiology and EEG-EG findings are discussed and compared with those published in the liter...

journal_title：Acta neurologica Belgica

authors： Monté CP,de Krom MC,Weber WE,de Zwaan C,van Kranen-Mastenbroek VH

更新日期：2007-03-01 00:00:00

abstract：:CADASIL is an autosomal dominant inherited arteriopathy caused by a point mutation in the Notch3 gene. Classically, it is characterised by recurrent ischemic strokes, often resulting in mental decline. Intracerebral haemorrhages in CADASIL have rarely been reported. We describe a young male with a genetically proven C...

journal_title：Acta neurologica Belgica

authors： Werbrouck BF,De Bleecker JL

更新日期：2006-12-01 00:00:00

abstract：:Epilepsy is a neurological disorder consisting of recurrent seizures, resulting from excessive, uncontrolled electrical activity in the brain. Epilepsy treatment is successful in the majority of the cases; however; still one third of the epilepsy patients are refractory to treatment. Besides the ongoing research on th...

journal_title：Acta neurologica Belgica

authors： Dedeurwaerdere S,Vonck K,De Herdt V,Waterschoot L,De Smedt T,Raedt R,Wyckhuys T,Legros B,Van Hese P,Van Laere K,Delbeke J,Wadman W,Boon P

更新日期：2006-06-01 00:00:00

abstract：:High resolution MRI is very important in the evaluations of patients with intractable temporal lobe epilepsy in preoperative investigations. Morphologic abnormalities on cranial MRI usually indicate the epileptogenic focus. Intractable TLE patients who have normal cranial MRI or bilateral hippocampal atrophy may have ...

journal_title：Acta neurologica Belgica

authors： Gomceli YB,Erdem A,Bilir E,Kutlu G,Kurt S,Erden E,Karatas A,Erbas C,Serdaroglu A

更新日期：2006-03-01 00:00:00

abstract：UNLABELLED:Although there only have been a limited number of double-blind, placebo controlled trials, antipsychotics are considered to be effective drugs for the treatment of tics in Gilles de la Tourette syndrome (GTS). Evidence concerning the efficacy of olanzapine and other atypical antipsychotics in the treatment o...

journal_title：Acta neurologica Belgica

authors： Van den Eynde F,Naudts KH,De Saedeleer S,van Heeringen C,Audenaert K

更新日期：2005-12-01 00:00:00

abstract：:Imaging neurotransmission in vivo using positron emission tomography (PET) is a rapidly expanding clinical science. The present review summarizes the actual contribution of PET imaging to clinical problems in movement and seizure disorders and dementia. ...

journal_title：Acta neurologica Belgica

authors： Garraux G,Salmon E

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Increased intima-media thickness (IMT) of the common carotid arteries (CCA) and elevated levels of highly sensitive C-reactive protein (hsCRP) are both shown to be associated with the occurrence of stroke. We investigated whether elevated hsCRP level is a risk factor for the increased IMT of the CCA independ...

journal_title：Acta neurologica Belgica

authors： Benbir G,Bozluolcay M,Ince B

更新日期：2005-06-01 00:00:00

abstract：:Epilepsy and psychiatric diseases are frequent comorbidities. Psychoses in patients with epilepsy have special physiopathology and several clinical presentations and prognoses. Their treatments are also specific, according to the specific diagnosis. This paper represents the summary of a consensus meeting held in Nove...

journal_title：Acta neurologica Belgica

authors： Tugendhaft P,Ansseau M,de Borchgrave V,Delvaux V,de Tourtchaninoff M,Dubru JM,Floris M,Foulon M,Grisar T,Hmaimess G,Legros B,Mahieu B,Ossemann M,Sadzot B,van Ruckevorsel K,Verheulpen D

更新日期：2005-03-01 00:00:00

abstract：:Proposals about the regulations and medical criteria concerning epilepsy and driving, originally drawn up by the Commission on Epilepsy and Risk from the Belgian League against Epilepsy were discussed and amended by a panel of representatives of several scientific societies and of all Belgian universities in order to ...

journal_title：Acta neurologica Belgica

authors： Schmedding E,Belgian Working Group on Epilepsy and Driving.

更新日期：2004-06-01 00:00:00

abstract：:In this study the role of DBS in advanced Parkinson disease (PD) is re-evaluated and new indications in the field of movement disorders are explored. The authors performed unilateral pallidal stimulation in 26 patients with advanced PD. At long-term follow-up review, the motor effect is unsatisfying. The authors concl...

journal_title：Acta neurologica Belgica

authors： Visser-Vandewalle V,Temel Y,van der Linden Ch,Ackermans L,Beuls E

更新日期：2004-03-01 00:00:00

abstract：:As dystonia may represent a severe disease with possible fatal outcome or physical or social incapacity, and considering the limited efficacy of drug treatments (excepted doparesponsive dystonia), efforts have been made since the 1950s to propose alternative treatment. In this paper, an overview of the works done by n...

journal_title：Acta neurologica Belgica

authors： Vercueil L

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:In carotid artery dissections, local and ischemic manifestations usually occur within days or weeks. In some cases, persistent extracranial aneurysms cause thromboembolic complications even years after the initial event. The management of these aneurysms is still controversial. CASE DESCRIPTION:We report th...

journal_title：Acta neurologica Belgica

authors： Peeters A,Goffette P,Dorban S,Sindic CJ,Cosnard G

更新日期：2003-09-01 00:00:00

abstract：:In recent years, different research lines have examined the epileptogenic process in order to understand the different stages in this process, and with the hope that early recognition and intervention could prevent chronic epilepsy in patients with epileptic seizures. In animals, acquired epilepsy is studied most comm...

journal_title：Acta neurologica Belgica

authors： Lagae L,Buyse G,Ceulemans B,Claeys P,Dedeurwaerdere S,de Meirleir L,Hauman R,Janssen A,Schmedding E,Verhelst H,Vonck K

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:To study the impact of cognitive impairment and severity of dementia on the quality of life (QoL) of patients and their caregivers. DESIGN:Descriptive cross-sectional study within the NAtional Dementia Economic Study. SETTING:231 general practices and 15 specialist clinics in Belgium. SUBJECTS:605 patients...

journal_title：Acta neurologica Belgica

authors： Kurz X,Scuvee-Moreau J,Vernooij-Dassen M,Dresse A

更新日期：2003-03-01 00:00:00

abstract：:Functional brain imaging studies, such as positron emission tomography and functional nuclear magnetic resonance imaging, are based on the regional increases in cerebral blood flow, glucose consumption and oxygen consumption that are associated with regional increases in neuronal activity. The cellular basis of the si...

journal_title：Acta neurologica Belgica

authors： Paemeleire K

更新日期：2002-12-01 00:00:00

abstract：:In this study, serum triglyceride, total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), very low-density lipoprotein cholesterol (VLDL-C), vitamin B12 and folic acid levels were studied in children with epilepsy who had been receiving long-term valproate (V...

journal_title：Acta neurologica Belgica

authors： Geda G,Caksen H,Içağasioğlu D

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Meningiomas are common tumors of the central nervous system. Although most are benign tumors, approximately 10% show a histologic progression to a higher malignancy grade similar to atypical (GII) and anaplastic (GIII) meningiomas. Monosomy 22q12 is the most frequent genetic alteration detected in these tumo...

journal_title：Acta neurologica Belgica

authors： Arslantas A,Artan S,Oner U,Durmaz R,Müslümanoğlu H,Atasoy MA,Başaran N,Tel E

更新日期：2002-06-01 00:00:00

abstract：:Neuropathology plays a crucial role in the phenotypic individualization of hereditary disorders affecting the central and peripheral nervous system even if molecular genetics represents the most essential step in describing the genotypes. The neuropathological description of phenotypes and genotypes can be used for re...

journal_title：Acta neurologica Belgica

authors： Martin JJ,Ceuterick C

更新日期：2002-03-01 00:00:00

abstract：:We report a 44-year-old female patient without any familial history of dementia presenting with increasing disturbances in behaviour and language followed by a progressive cognitive deterioration. Neuropsychological evaluation revealed a significant impairment on frontal lobe tests. A brain PET scan disclosed a severe...

journal_title：Acta neurologica Belgica

authors： Michotte A,Goldman S,Tugendhaft P,Zegers de Beyl D

更新日期：2001-12-01 00:00:00

abstract：:Cyclosporine-A is a highly potent immunosuppressive agent for solid organ transplantation, but has many side effects including nephrotoxicity, hypertension, gum hyperplasia, hepatotoxicity, and neurotoxicity. Neurotoxicity is a less known toxic effect. The pathogenesis of this effect is unclear. However, it has been p...

journal_title：Acta neurologica Belgica

authors： Derici U,Arinsoy T,Sindel S,Tali T,Leventoglu A,Sert S

更新日期：2001-06-01 00:00:00

abstract：:The concept of a group of headaches whose pathophysiological focus revolves around the trigeminal-autonomic reflex fills a useful gap in characterising a number of primary headache syndromes. Broadly, these syndromes involve activation of trigeminovascular nociceptive pathways with reflex cranial autonomic activation....

journal_title：Acta neurologica Belgica

authors： Goadsby PJ

更新日期：2001-03-01 00:00:00

abstract：:We report an unusual case of probable progressive multifocal leukoencephalopathy (PML), who initially presented with a right-sided movement disorder, including upper limb dystonia, tremor, and dyspraxia, reminiscent of corticobasal degeneration. In the further course, the patient developed disorientation, confusion, a...

journal_title：Acta neurologica Belgica

authors： Van Zanducke M,Dehaene I

更新日期：2000-12-01 00:00:00

abstract：:Inflammatory demyelinating polyradiculoneuropathy causes a spectrum of conditions ranging from acute (Guillain-Barré syndrome), through subacute to chronic forms. The pathogenesis of acute forms is related to antibody responses against glycolipid epitopes which mimic bacterial, especially Campylobacter jejuni, structu...

journal_title：Acta neurologica Belgica

authors： Hughes RA

更新日期：2000-09-01 00:00:00

abstract：:Neuropraxia of the cervical spinal cord is a rare condition which is almost exclusively reported in American football players following cervical hyperextension or hyperflexion trauma. In this entity-neurological symptoms of both arms and legs for a period of up to 15 minutes are observed with complete recovery. We rep...

journal_title：Acta neurologica Belgica

authors： Bernsen HJ,Koetsveld A,Frenken CW,van Norel GJ

更新日期：2000-06-01 00:00:00

abstract：:A 47-year-old female developed proximal limb weakness after hysterectomy for uterine fibromatosis. Muscle strength slowly improved, but relapse occurred at age 52. She presented with progressive gait difficulty, proximal limb weakness, and painful calves. Family history was not contributory. Cranial nerves, deep tendo...

journal_title：Acta neurologica Belgica

authors： Deconinck N,Laterre EC,Van den Bergh PY

更新日期：2000-03-01 00:00:00

abstract：:Over the last decade, many new drugs have been added to the therapeutic armamentarium for epilepsy. These drugs differ considerably in their mechanisms of action and, consequently, in their spectrum of efficacy against various seizure types. Oxcarbazepine, gabapentin, tiagabine and vigabatrin are especially useful in ...

journal_title：Acta neurologica Belgica

authors： Perucca E

更新日期：1999-12-01 00:00:00

abstract：:In contrast to the classic, slowly progressive polyneuropathy in alcoholic patients, acute forms, clinically mimicking Guillain-Barré syndrome, are rare. We present a patient who developed motor weakness and sensory loss in all four limbs within four days. Laboratory data were consistent with long-term alcohol abuse a...

journal_title：Acta neurologica Belgica

authors： Vandenbulcke M,Janssens J

更新日期：1999-09-01 00:00:00

abstract：:Spontaneous but incomplete remyelination is observed after a demyelinating lesion. We know since ten years now that oligodendrocyte progenitors, (OP) and totipotent neural stem cells remain present in the central nervous system of adult mammals. Moreover, these OP are more likely the cellular source of remyelinating c...

journal_title：Acta neurologica Belgica

authors： Rogister B,Belachew S,Moonen G

更新日期：1999-03-01 00:00:00

abstract：PURPOSE:A retrospective evaluation of the ictal temporal tracer uptake and the perfusion pattern in other neo- and subcortical structures was performed to define typical extratemporal changes of rCBF that might further aid the differentiation of temporal and extratemporal seizures. METHOD:Ictal and interictal rCBF bra...

journal_title：Acta neurologica Belgica

authors： Menzel C,Grünwald F,Klemm E,Ruhlmann J,Elger CE,Biersack HJ

更新日期：1998-12-01 00:00:00

abstract：:Spinal cord stimulation is an accepted treatment for neuropathic pain. Technical advances in electrode design and better patient selection have led to better and sustained pain control by these devices. Multilead electrical stimulation is the latest innovation in implantable electrostimulation (Mattrix, Medtronic Minn...

journal_title：Acta neurologica Belgica

authors： Devulder J,De Laat M,Rolly G

更新日期：1998-06-01 00:00:00

abstract：:Serum and cerebrospinal fluid (CSF) of 13 patients have been examined to confirm and precise the diagnosis of herpes simplex virus encephalitis (HSVE). By amplifying the DNA with a nested polymerase chain reaction (PCR), we could demonstrate the herpetic origin of these cases of encephalitis. DNA of HSV type 1 or type...

journal_title：Acta neurologica Belgica

authors： Monteyne P,Laterre EC,Sindic CJ

更新日期：1997-12-01 00:00:00